The Historical Case for and the Future Study of Antibiotic-Resistant Scrub Typhus
Scrub typhus is an acute, and sometimes fatal, human febrile illness, typically successfully treated using chloramphenicol or one of the tetracyclines.Over the past several years, descriptions of strains of Orientia tsutsugamushi with reduced susceptibility to antibiotics have appeared.Because case-fatality ratios approached 50% during the pre-anti